In obstructive rest apnea (OSA), doses as much as 250 mg/day happen to be nicely-tolerated but there is no consistent evidence of extra profit further than the a hundred and fifty mg/working day.
For oral dosage sort (tablets): For narcolepsy or obstructive rest apnea/hypopnea syndrome: Adults and teenagers 17 yrs of age and more mature—200 milligrams (mg) when a day, in the morning. Your medical professional could boost your dose as essential. Teens and children young than 17 decades of age—Use and dose has to be determined by your physician.
Discontinue interfering medications for at least 5 half-lives just before administration of possibly the dosimetry or an iobenguane dose. Do not administer these medications until finally at the least 7 days just after Each and every iobenguane dose.
Check Closely (one)triclabendazole will boost the amount or result of modafinil by impacting hepatic enzyme CYP2C19 metabolism.
Belzutifan can be a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors might enhance incidence or severity of adverse results. Observe for anemia and hypoxia and decrease belzutifan dose as advisable.
Using this drugs with any of the next medicines isn't recommended. Your health care provider may well make a decision not to deal with you with this medication or change a number of the other medicines you take.
Coadministration of encorafenib with sensitive CYP3A4 substrates may possibly end in elevated toxicity or reduced efficacy of these agents.
Dose changes of those medication as well as other drugs that are substrates for CYP2C19 may very well be required if modafinil is coadministered
nelfinavir will raise the degree or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
No major adjustments in entire body excess weight have been noticed in clinical trials, although diminished urge for food and weight reduction are actually observed in small children and adolescents.
Other medicines may well connect with modafinil, such as prescription and in excess of-the-counter medicines, nutritional vitamins, and herbal products and solutions. Convey to Each individual of your respective health care vendors about all medicines you utilize now and any medication you start or quit using.
It is website important to tell your medical doctor in case you develop into Expecting. Your health practitioner might want you to hitch a pregnancy registry for clients having this drugs.
This medication is on the market only with the health care provider's prescription. This product is available in the following dosage sorts:
cannabidiol will improve the stage or result of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Intently. Consider reducing the dose of delicate CYP2C19 substrates, as clinically acceptable, when coadministered with cannabidiol.